Gambling is an ancient human activity, but the gambling industry as we know it started out in the 1960s. First and foremost, the most significant difference has to do with whether we’re talking about online operators or traditional venues. The various ways casinos pay out large sums of money depending on several factors. How Casinos Pay Out Large Sums Of Money: A Detailed Guide The methods with which casinos pay out large sums of money range from one operator to the next.